10 Most Uplifting Prayers for Your Sister


What a blessing it is to have sisters! They’re one of the most extraordinary gifts a God can bestow upon your life.

However, as supportive and loving as they can be, they too have their own struggles and problems to deal with. 

When you notice your sister going through tough times, the best thing to do is to pray and ask God to embrace her into His loving arms.

If you’re unsure how to put your heart into words, this article contains prayers for sister that are sure to reach God’s ear and bless your beloved sister.

A Prayer Of Gratitude For My Sister


I thank You for my sister and the beautiful bond that is between us.
I am grateful for the gift of my family because Your Word says that you place the solitary in families.

I am thankful for all the moments we’ve shared as siblings and all the hurdles we’ve crossed together. Thank You for her growth throughout the years. I can’t appreciate You enough.

Lord, I pray that You would draw her closer to You and lead her in all that she does.
Be her strength and a constant light unto her path.

In Jesus’ name, amen.

Strength Prayer For My Sister

Heavenly Father,

You alone know the secret thoughts and struggles of every man. You see our pain and know every tear that drops from our eyes. My sister and I are close, but I do not know her pain and challenges as you do. You alone fully see the battles she is waging within her heart and soul.

Father, please be her strength in her times of doubt and hardship. Hold her close in her moments of despair. Lift every burden that weighs on her heart and give her rest of mind.

Fill her with a constant reminder that You are with her no matter what. Let her feel Your assuring presence in every season, giving her faith to finish strong. Grant her a fresh supply of strength daily.

In Jesus’ name, Amen.

Prayer For Sister’s Health


As I come before Your presence today, I make this healing prayer for my sister for strength. Father, be with her and grant her good health of mind and body.

Your Word tells us that by Your stripes, we have already been healed. Through Your sacrifice, we have the gift of good health.

Today I receive this gift on behalf of my sister. May no illness can come near her dwelling place. No matter what happens, physical well-being shall always be her lot by Your power.

Grant her a long life, Lord, that will be dedicated to You and advancing Your Kingdom.
Thank You for Your never-ending love.

In Jesus’ name, Amen.

Prayer For My Sister Having Surgery

Heavenly Father,

I come before You to thank You for my wonderful sister. Thank You for the blessing of her love and friendship.

Father my sister is preparing to have surgery and I know that she may be scared at this point. I pray that You would quiet the storm in her heart and give her peace.

As she goes into surgery, I pray that You fill every person in the operating room with Your boundless wisdom. O great Physician, direct the surgeon’s hands. Let her feel Your presence with her comforting her as she falls asleep.

When she comes out of surgery, Lord, please surround her with a blanket of ease so that her pain will be eased.

Guide her through her recovery process and give her the strength to push through this time. Teach her to walk with your timing and intent so that she can fully understand Your will and Your purpose for her life.

In Jesus’ name, Amen.

Prayer For My Sister-in-law

Dear God,

Thank you for my sister-in-law and her family. Teach me to be a supportive person to her.
Help me to support and love her in the way that I should. Give me the heart to accommodate her so that we can be the family You have called us to be.

Bless her in all her endeavors and give her an understanding of Your love and mercy working in her life. Keep her safe from the eyes of the enemy.
I honor You for all the grace and mercy You have shown to her.

In Jesus’ name, amen.

Prayer For A Lost Sister

King of glory,

Thank you for my sister and the love for her you have planted in my heart. Regardless of our differences, misunderstandings, and different lifestyles, I love her very much for she is Your masterpiece. But I recognize that you cherish her far more than I ever can.

Lord, please draw her unbelieving heart to You. Help her to realize the love You have for her.
Help her to know the fragrance of Your Presence and realize that there’s nothing else like it.
It makes me sad that she hasn’t received the Gospel nor experienced life in You and the joy that comes with it. Take her heart of flesh and give her a heart of flesh that responds to you. Help her to know You and love You through and through.

Open her eyes that she may see and open her ears that she may hear. Draw her into Jesus’ arms.


Prayer For Sister’s Protection

My Sweet Lord,

I bring my sister before You today. As much as I want to, I have no power to shield her from the evils of life, except in the place of prayer. You’re the only one I can trust with my sister. You’re the only one who can truly protect her. You alone have the power to keep her safe from all the wiles of the enemy. Her life belongs to You and You alone.

Today Lord, I commit my sister to Your loving care and refuge. Take her under your shield and protect her from all forms of evil intentions. Be her Defender against those who seek to bring her down. I ask that you guide and lead her in the right direction. And in times of trouble, be her Deliverer. I pray that you guide and protect her as she goes through life here. I ask that she abides under Your shadow.

I bring my sister under the unprecedented covering of Your blood. May her footsteps be ordered in You. The eyes of the enemy shall be blinded when she comes into view, and I declare that her life is fully covered in You.

Thank You, Lord, because I know she’s safe, and that you care for her much more than I do.

In Jesus’ name, I pray. Amen.

Birthday Prayer For My Sister

Heavenly Father,

I thank you for the life of my sister. I thank you for keeping her safely up until this beautiful day. Thank you for the grace you’ve given her to live and turn a year older in you.

Oh Lord, I ask for even more grace as she enters this new phase of her destiny. Let her know you more. Let her uncover destiny and continue to grow and soar. I pray that You bless her beyond her expectations. Let all her dreams begin to align with all You’ve written about her in the volume of the books. Let her life reflect Your thoughts towards her.

I pray that my sister will fulfill her purpose. May everything she sets out to do prosper. May her heart always be in the right place at the right time. May all honor her.

In Jesus’ name, I pray. Amen.

Blessing For Sister’s Growth In Christ


I bless my sister today. I pray that with each day that passes, her walk with You deepens.

May she constantly walk by the leading of Your Spirit. Help her to grow in Your knowledge and faith. So that in dark times, she will learn to lean on You and Your strength.

Give her the understanding that her walk with You is a process of refining so that she may be able to submit herself to it.

Give her the desire to be intimate with You in daily prayer and the grace to study Your Word and live by its truth. Let her thoughts and will be aligned with Yours. Give her the courage to obey you every step of the way, even when it’s hard. Let her grow in excellence, contriteness, humility and patience. Use her mightily to shine light in the darkness of this world. May she represent you in all she does and says.

In Jesus’ name, Amen.

Prayer For Sister’s Success

Dearest Father,

I thank You for all that You have given us and all that we are. Today I pray for my sister and ask You to make her prosperous. Give her victory in everything she does. Bless the works of her hands. Increase her capacity and grant her success in life. Help her to push for all her dreams to become reality.
Grant her the desires of her heart and help her fulfill her full potential.

May she be a model of excellence among her peers. Help her understand the advantage she has in You over everyone else. Make her a testimony of Your unfailing love and righteousness. Finally, teach her to return all the glory to you, both in success and in temporary failures.

In Jesus’ name, Amen.

Final Thoughts

Prayers are so powerful and there’s no greater gift you can give to your sister than asking God for His guidance in her life. That’s why it’s so important that you keep them in your daily prayers. 

Apart from this, it is also great to constantly let them know you love them by being there when they need you. Calls, visits, and gifts are a good way to make your sisters feel appreciated.

Finally, when you pray, pray with faith in God’s willingness and ability to work things together for their good. It doesn’t matter whether you say these prayers for sister in secret, or together with them, God will always give an answer according to His will.